3R94
AKR1C3 complex with flurbiprofen
Summary for 3R94
Entry DOI | 10.2210/pdb3r94/pdb |
Descriptor | Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (2R)-2-(3-fluoro-4-phenyl-phenyl)propanoic acid, ... (5 entities in total) |
Functional Keywords | tim barrel, flurbiprofen, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P42330 |
Total number of polymer chains | 1 |
Total formula weight | 39027.10 |
Authors | Yosaatmadja, Y.,Teague, R.M.,Flanagan, J.U.,Squire, C.J. (deposition date: 2011-03-24, release date: 2012-05-02, Last modification date: 2023-09-13) |
Primary citation | Flanagan, J.U.,Yosaatmadja, Y.,Teague, R.M.,Chai, M.Z.,Turnbull, A.P.,Squire, C.J. Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3. Plos One, 7:e43965-e43965, 2012 Cited by PubMed: 22937138DOI: 10.1371/journal.pone.0043965 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.013 Å) |
Structure validation
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