3R77

Crystal structure of the D38A mutant of isochorismatase PhzD from Pseudomonas fluorescens 2-79 in complex with 2-amino-2-desoxyisochorismate ADIC

Summary for 3R77

Entry DOI	10.2210/pdb3r77/pdb
Related	3R74 3R75 3R76
Descriptor	Probable isochorismatase, (5S,6S)-6-amino-5-[(1-carboxyethenyl)oxy]cyclohexa-1,3-diene-1-carboxylic acid, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	hydrolase, isochorismatase, phenazine biosynthesis
Biological source	Pseudomonas fluorescens
Total number of polymer chains	2
Total formula weight	47089.13
Authors	Li, Q.A.,Mavrodi, D.V.,Thomashow, L.S.,Roessle, M.,Blankenfeldt, W. (deposition date: 2011-03-22, release date: 2011-03-30, Last modification date: 2024-02-21)
Primary citation	Li, Q.A.,Mavrodi, D.V.,Thomashow, L.S.,Roessle, M.,Blankenfeldt, W. Ligand Binding Induces an Ammonia Channel in 2-Amino-2-desoxyisochorismate (ADIC) Synthase PhzE. J.Biol.Chem., 286:18213-18221, 2011 Cited by PubMed: 21454481 DOI: 10.1074/jbc.M110.183418 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation