3R3O

Crystal structure of Staphylococcal nuclease variant Delta+PHS T62A at cryogenic temperature and with high redundancy

Summary for 3R3O

Entry DOI	10.2210/pdb3r3o/pdb
Related	3BDC 3MEH 3MHB 3MVV 3MXP 3MZ5
Descriptor	Thermonuclease, CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywords	hyperstable variant, pdtp, pressure, cavity, hydrolase
Biological source	Staphylococcus aureus
Cellular location	Nuclease A: Secreted. Nuclease B: Membrane: P00644
Total number of polymer chains	1
Total formula weight	16555.70
Authors	Caro, J.A.,Schlessman, J.L.,Garcia-Moreno E., B. (deposition date: 2011-03-16, release date: 2011-03-30, Last modification date: 2023-09-13)
Primary citation	Roche, J.,Caro, J.A.,Norberto, D.R.,Barthe, P.,Roumestand, C.,Schlessman, J.L.,Garcia, A.E.,Garcia-Moreno E, B.,Royer, C.A. Cavities determine the pressure unfolding of proteins. Proc.Natl.Acad.Sci.USA, 109:6945-6950, 2012 Cited by PubMed: 22496593 DOI: 10.1073/pnas.1200915109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation