Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3R30

MK2 kinase bound to Compound 2

Summary for 3R30
Entry DOI10.2210/pdb3r30/pdb
Related3R1N 3R2B 3R2Y
DescriptorMAP kinase-activated protein kinase 2, 1-(2-aminoethyl)-3-[2-(quinolin-3-yl)pyridin-4-yl]-1H-pyrazole-5-carboxylic acid (2 entities in total)
Functional Keywordskinase domain with bound inhibitor, kinase domain, phosphotransferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight37252.04
Authors
Oubrie, A.,Fisher, M. (deposition date: 2011-03-15, release date: 2011-05-25, Last modification date: 2024-02-21)
Primary citationBarf, T.,Kaptein, A.,Wilde, S.,Heijden, R.,Someren, R.,Demont, D.,Schultz-Fademrecht, C.,Versteegh, J.,Zeeland, M.,Seegers, N.,Kazemier, B.,Kar, B.,Hoek, M.,Roos, J.,Klop, H.,Smeets, R.,Hofstra, C.,Hornberg, J.,Oubrie, A.
Structure-based lead identification of ATP-competitive MK2 inhibitors.
Bioorg.Med.Chem.Lett., 21:3818-3822, 2011
Cited by
PubMed: 21565500
DOI: 10.1016/j.bmcl.2011.04.018
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.2 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon