3QMO

X-ray crystal structure of NS-398 bound to the cyclooxygenase channel of cyclooxygenase-2

Summary for 3QMO

Entry DOI	10.2210/pdb3qmo/pdb
Related	3HS5 3HS6 3HS7 3LN1 3NT1 6COX
Descriptor	Prostaglandin G/H synthase 2, alpha-D-mannopyranose, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
Functional Keywords	biological dimer, oxidoreductase, dimer, n-glycosylation, monotopic membrane protein
Biological source	Mus musculus (mouse)
Total number of polymer chains	2
Total formula weight	144946.48
Authors	Vecchio, A.J.,Malkowski, M.G. (deposition date: 2011-02-04, release date: 2011-08-03, Last modification date: 2023-09-13)
Primary citation	Vecchio, A.J.,Malkowski, M.G. The structure of NS-398 bound to cyclooxygenase-2. J.Struct.Biol., 176:254-258, 2011 Cited by PubMed: 21843643 DOI: 10.1016/j.jsb.2011.07.019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation