3QDA

Crystal structure of W95L beta-2 microglobulin

Summary for 3QDA

Entry DOI	10.2210/pdb3qda/pdb
Descriptor	Beta-2-microglobulin, TRIETHYLENE GLYCOL (3 entities in total)
Functional Keywords	tryptophan, immunoglobin, beta-sandwich, hydrophobic pocket, amyloidosis, dra, mhc class i, immune system
Biological source	Homo sapiens (human)
Cellular location	Secreted: P61769
Total number of polymer chains	1
Total formula weight	11956.48
Authors	Ricagno, S.,Bellotti, V.,Bolognesi, M. (deposition date: 2011-01-18, release date: 2011-06-29, Last modification date: 2023-09-13)
Primary citation	Raimondi, S.,Barbarini, N.,Mangione, P.,Esposito, G.,Ricagno, S.,Bolognesi, M.,Zorzoli, I.,Marchese, L.,Soria, C.,Bellazzi, R.,Monti, M.,Stoppini, M.,Stefanelli, M.,Magni, P.,Bellotti, V. The two tryptophans of beta2-microglobulin have distinct roles in function and folding and might represent two independent responses to evolutionary pressure. BMC Evol Biol, 11:159-159, 2011 Cited by PubMed: 21663612 DOI: 10.1186/1471-2148-11-159 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.57 Å)

Structure validation