3Q6E

Human insulin in complex with cucurbit[7]uril

Summary for 3Q6E
DescriptorInsulin A chain, Insulin B chain, cucurbit[7]uril, ... (4 entities in total)
Functional Keywordsinsulin, cucurbit[7]uril, cucurbituril, synthetic, host, phenylalanine, supramolecular, recognition, carbohydrate metabolism, cleavage on pair of basic residues, diabetes mellitus, disease mutation, disulfide bond, glucose metabolism, hormone, secreted
Biological sourceHomo sapiens (human)
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Cellular locationSecreted: P01308 P01308
Total number of polymer chains4
Total formula weight12798.26
Authors
Chinai, J.M.,Taylor, A.B.,Hargreaves, N.D.,Ryno, L.M.,Morris, C.A.,Hart, P.J.,Urbach, A.R. (deposition date: 2010-12-31, release date: 2011-04-20, Last modification date: 2014-02-19)
Primary citationChinai, J.M.,Hargreaves, N.D.,Hart, P.J.,Morris, C.A.,Ryno, L.M.,Taylor, A.B.,Urbach, A.R.
Molecular recognition of insulin by a synthetic receptor.
J.Am.Chem.Soc., 133:8810-8813, 2011
PubMed: 21473587
DOI: 110.1021/ja201581x
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.05 Å)
Structure validation
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PDB entries from 2021-06-23