3O73
Crystal structure of quinone reductase 2 in complex with the indolequinone MAC627
Summary for 3O73
Entry DOI | 10.2210/pdb3o73/pdb |
Related | 1QR2 |
Descriptor | Ribosyldihydronicotinamide dehydrogenase [quinone], ZINC ION, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total) |
Functional Keywords | quinone reductase 2, nqo2, oxidoreductase, flavoprotein, indolequinone mac627, fad, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P16083 |
Total number of polymer chains | 2 |
Total formula weight | 56145.62 |
Authors | Dufour, M.,Yan, C.,Colucci, M.A.,Siegel, D.,Li, Y.,De Matteis, C.I.,Ross, D.,Moody, C.J. (deposition date: 2010-07-30, release date: 2011-05-11, Last modification date: 2023-09-06) |
Primary citation | Dufour, M.,Yan, C.,Siegel, D.,Colucci, M.A.,Jenner, M.,Oldham, N.J.,Gomez, J.,Reigan, P.,Li, Y.,De Matteis, C.I.,Ross, D.,Moody, C.J. Mechanism-Based Inhibition of Quinone Reductase 2 (NQO2): Selectivity for NQO2 over NQO1 and Structural Basis for Flavoprotein Inhibition. Chembiochem, 12:1203-1208, 2011 Cited by PubMed: 21506232DOI: 10.1002/cbic.201100085 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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