3O2D
Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody
Summary for 3O2D
Entry DOI | 10.2210/pdb3o2d/pdb |
Descriptor | ibalizumab light chain, ibalizumab heavy chain, T-cell surface glycoprotein CD4, ... (4 entities in total) |
Functional Keywords | immunoglobulin fold, hiv-1 primary receptor, t cell coreceptor, monoclonal antibody, membrane, immune system |
Biological source | Mus musculus (mouse) More |
Cellular location | Cell membrane; Single-pass type I membrane protein: P01730 |
Total number of polymer chains | 3 |
Total formula weight | 69577.77 |
Authors | Freeman, M.M.,Seaman, M.S.,Rits-Volloch, S.,Hong, X.,Ho, D.D.,Chen, B. (deposition date: 2010-07-22, release date: 2010-12-22, Last modification date: 2011-07-13) |
Primary citation | Freeman, M.M.,Seaman, M.S.,Rits-Volloch, S.,Hong, X.,Kao, C.Y.,Ho, D.D.,Chen, B. Crystal Structure of HIV-1 Primary Receptor CD4 in Complex with a Potent Antiviral Antibody. Structure, 18:1632-1641, 2010 Cited by PubMed: 21134642DOI: 10.1016/j.str.2010.09.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
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