3NRI
Crystal structure of the C(30) carotenoid dehydrosqualene synthase from S. aureus complexed with dehydrosqualene (DHS)
Summary for 3NRI
Entry DOI | 10.2210/pdb3nri/pdb |
Related | 2ZCO 2ZCP 3NPR |
Descriptor | Dehydrosqualene synthase, (6E,10R,13S,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,11,13,14,18,22-octaene (2 entities in total) |
Functional Keywords | dehydrosqualene synthase, terpene, carotenoid, crtm, dhs, virulence factor, prenyl transferase, transferase |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 1 |
Total formula weight | 35194.18 |
Authors | Lin, F.-Y.,Liu, C.-I.,Liu, Y.-L.,Wang, K.,Zhang, Y.,Oldfield, E. (deposition date: 2010-06-30, release date: 2010-12-22, Last modification date: 2023-12-27) |
Primary citation | Lin, F.Y.,Liu, C.I.,Liu, Y.L.,Zhang, Y.,Wang, K.,Jeng, W.Y.,Ko, T.P.,Cao, R.,Wang, A.H.,Oldfield, E. Mechanism of action and inhibition of dehydrosqualene synthase. Proc.Natl.Acad.Sci.USA, 107:21337-21342, 2010 Cited by PubMed: 21098670DOI: 10.1073/pnas.1010907107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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