3NQU

Crystal structure of partially trypsinized (CENP-A/H4)2 heterotetramer

Summary for 3NQU

• Entry DOI: 10.2210/pdb3nqu/pdb
• Related: 3NQJ
• Descriptor: Histone H3-like centromeric protein A, Histone H4, SULFATE ION, ... (4 entities in total)
• Functional Keywords: alpha helix, histone fold, centromere, dna binding protein
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P49450 P62805
• Total number of polymer chains: 2
• Total formula weight: 27898.37

Authors

Sekulic, N.,Black, B.E. (deposition date: 2010-06-29, release date: 2010-08-25, Last modification date: 2023-09-06)

• Primary citation: Sekulic, N.,Bassett, E.A.,Rogers, D.J.,Black, B.E.; The structure of (CENP-A-H4)(2) reveals physical features that mark centromeres.; Nature, 467:347-351, 2010; PubMed: 20739937; DOI: 10.1038/nature09323

Experimental method

X-RAY DIFFRACTION (2.5 Å)