3N9G
Crystal structure of the Fab fragment of the human neutralizing anti-West Nile Virus MAb CR4354
Summary for 3N9G
Entry DOI | 10.2210/pdb3n9g/pdb |
EMDB information | 5190 |
Descriptor | Fab fragment of MAb CR4354, heavy chain, Fab fragment of MAb CR4354, light chain (3 entities in total) |
Functional Keywords | fab fragment, human neutralizing antibody, mab cr4354, immune system, anti-west nile virus |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 47653.86 |
Authors | Kaufmann, B.,Rossmann, M.G. (deposition date: 2010-05-29, release date: 2010-11-24, Last modification date: 2023-09-06) |
Primary citation | Kaufmann, B.,Vogt, M.R.,Goudsmit, J.,Holdaway, H.A.,Aksyuk, A.A.,Chipman, P.R.,Kuhn, R.J.,Diamond, M.S.,Rossmann, M.G. Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354. Proc.Natl.Acad.Sci.USA, 107:18950-18955, 2010 Cited by PubMed: 20956322DOI: 10.1073/pnas.1011036107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.434 Å) |
Structure validation
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