3MOQ

Amyloid beta(18-41) peptide fusion with new antigen receptor variable domain from sharks

Summary for 3MOQ

Entry DOI	10.2210/pdb3moq/pdb
Descriptor	New antigen receptor variable domain,P3(40) peptide from Amyloid beta A4 protein,New antigen receptor variable domain (2 entities in total)
Functional Keywords	ab-ignar, ab-12y-2, receptor, amyloid, glycoprotein, membrane, protease inhibitor, serine protease inhibitor, transmembrane, amyloid beta fusion with ignar, chimera of immune system and amyloid peptide, immune system, neuropeptide
Biological source	Orectolobus maculatus (spotted wobbegong) More
Total number of polymer chains	4
Total formula weight	53864.52
Authors	Streltsov, V.A. (deposition date: 2010-04-23, release date: 2011-02-16, Last modification date: 2023-11-01)
Primary citation	Streltsov, V.A.,Varghese, J.N.,Masters, C.L.,Nuttall, S.D. Crystal Structure of the Amyloid-{beta} p3 Fragment Provides a Model for Oligomer Formation in Alzheimer's Disease J.Neurosci., 31:1419-1426, 2011 Cited by PubMed: 21273426 DOI: 10.1523/JNEUROSCI.4259-10.2011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.054 Å)

Structure validation