3MI3

Homocitrate Synthase Lys4 bound to Lysine

Replaces:  3L90

Summary for 3MI3

• Entry DOI: 10.2210/pdb3mi3/pdb
• Related: 3IVS 3IVT 3IVU
• Descriptor: Homocitrate synthase, mitochondrial, LYSINE, ZINC ION, ... (5 entities in total)
• Functional Keywords: tim barrel, metalloprotein, transferase, claisen condensation, amino-acid biosynthesis, lysine biosynthesis
• Biological source: Schizosaccharomyces pombe (Fission yeast)
• Cellular location: Mitochondrion (Potential): Q9Y823
• Total number of polymer chains: 2
• Total formula weight: 93981.17

Authors

Bulfer, S.L.,Scott, E.M.,Pillus, L.,Trievel, R.C. (deposition date: 2010-04-09, release date: 2010-04-28, Last modification date: 2023-09-06)

• Primary citation: Bulfer, S.L.,Scott, E.M.,Pillus, L.,Trievel, R.C.; Structural Basis for L-lysine Feedback Inhibition of Homocitrate Synthase; J.Biol.Chem., 285:10446-10453, 2010; PubMed: 20089861

Experimental method

X-RAY DIFFRACTION (2.38 Å)