3MEH

Crystal structure of Staphylococcal nuclease variant Delta+PHS I92A at cryogenic temperature

Summary for 3MEH

Entry DOI	10.2210/pdb3meh/pdb
Related	3BDC 3M87 3MHB
Descriptor	Thermonuclease, CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywords	hyperstable variant, hydrolase, pdtp, cavity, pressure
Biological source	Staphylococcus aureus
Cellular location	Nuclease A: Secreted. Nuclease B: Membrane: P00644
Total number of polymer chains	1
Total formula weight	16543.65
Authors	Caro, J.A.,Schlessman, J.L.,Garcia-Moreno, E.B.,Heroux, A. (deposition date: 2010-03-31, release date: 2011-03-16, Last modification date: 2023-09-06)
Primary citation	Roche, J.,Caro, J.A.,Norberto, D.R.,Barthe, P.,Roumestand, C.,Schlessman, J.L.,Garcia, A.E.,Garcia-Moreno E, B.,Royer, C.A. Cavities determine the pressure unfolding of proteins. Proc.Natl.Acad.Sci.USA, 109:6945-6950, 2012 Cited by PubMed: 22496593 DOI: 10.1073/pnas.1200915109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation