3LKR

Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 2009 H1N1 swine origin strain

Summary for 3LKR

• Entry DOI: 10.2210/pdb3lkr/pdb
• Related: 3LKN 3LKO 3LKP 3LKQ 3LKS
• Descriptor: HLA class I histocompatibility antigen, B-35 alpha chain, Beta-2-microglobulin, NP418 epitope from 2009 swine-influenza strain, ... (4 entities in total)
• Functional Keywords: hla b*3501, np418 epitope, influenza, swine-flu, t cell immunity, disulfide bond, glycoprotein, host-virus interaction, immune response, membrane, mhc i, transmembrane, amyloid, amyloidosis, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P30685; Secreted: P61769
• Total number of polymer chains: 3
• Total formula weight: 44883.88

Authors

Gras, S.,Kedzierski, L.,Valkenburg, S.A.,Liu, Y.C.,Denholm, J.,Richards, M.,Rimmelzwaan, G.F.,Doherty, P.C.,Turner, S.J.,Rossjohn, J.,Kedzierska, K. (deposition date: 2010-01-27, release date: 2010-07-07, Last modification date: 2023-09-06)

• Primary citation: Gras, S.,Kedzierski, L.,Valkenburg, S.A.,Laurie, K.,Liu, Y.C.,Denholm, J.T.,Richards, M.J.,Rimmelzwaan, G.F.,Kelso, A.,Doherty, P.C.,Turner, S.J.,Rossjohn, J.,Kedzierska, K.; Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses.; Proc.Natl.Acad.Sci.USA, 107:12599-12604, 2010; PubMed: 20616031; DOI: 10.1073/pnas.1007270107

Experimental method

X-RAY DIFFRACTION (2 Å)