3L5N
Staphylococcal Complement Inhibitor (SCIN) in complex with Human Complement Component C3b
Summary for 3L5N
Entry DOI | 10.2210/pdb3l5n/pdb |
Related | 3L3O |
Descriptor | Complement C3, Staphylococcal complement inhibitor, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | complement alternate pathway, complement pathway, converstase, immune response, inflammatory response, innate immunity, secreted, virulence, immune evasion, immune system |
Biological source | Staphylococcus aureus More |
Cellular location | Secreted: P01024 P01024 Q931M7 |
Total number of polymer chains | 3 |
Total formula weight | 186374.63 |
Authors | Geisbrecht, B.V.,Garcia, B.L. (deposition date: 2009-12-22, release date: 2010-08-04, Last modification date: 2023-09-06) |
Primary citation | Garcia, B.L.,Ramyar, K.X.,Tzekou, A.,Ricklin, D.,McWhorter, W.J.,Lambris, J.D.,Geisbrecht, B.V. Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b. J.Mol.Biol., 402:17-29, 2010 Cited by PubMed: 20654625DOI: 10.1016/j.jmb.2010.07.029 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (7.536 Å) |
Structure validation
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