3KRQ
Crystal structure of the complex of lactoperoxidase with a potent inhibitor amino-triazole at 2.2a resolution
Summary for 3KRQ
Entry DOI | 10.2210/pdb3krq/pdb |
Related | 3GC1 |
Descriptor | Lactoperoxidase, DI(HYDROXYETHYL)ETHER, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total) |
Functional Keywords | heme, peroxidase, complex, antibiotic, antimicrobial, cleavage on pair of basic residues, disulfide bond, glycoprotein, hydrogen peroxide, iron, metal-binding, secreted, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Bos taurus (bovine) |
Total number of polymer chains | 1 |
Total formula weight | 71974.65 |
Authors | Singh, A.K.,Singh, N.,Sinha, M.,Kushwaha, G.S.,Kaur, P.,Srinivasan, A.,Sharma, S.,Singh, T.P. (deposition date: 2009-11-19, release date: 2010-05-26, Last modification date: 2023-11-01) |
Primary citation | Singh, A.K.,Singh, N.,Tiwari, A.,Sinha, M.,Kushwaha, G.S.,Kaur, P.,Srinivasan, A.,Sharma, S.,Singh, T.P. First structural evidence for the mode of diffusion of aromatic ligands and ligand-induced closure of the hydrophobic channel in heme peroxidases J.Biol.Inorg.Chem., 15:1099-1107, 2010 Cited by PubMed: 20461536DOI: 10.1007/s00775-010-0669-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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