3KNS
Bacillus cereus metallo-beta-lactamase Cys221Asp mutant, 20 mM Zn(II)
Summary for 3KNS
| Entry DOI | 10.2210/pdb3kns/pdb |
| Related | 1bc2 1bvt 3knr |
| Descriptor | Beta-lactamase 2, ZINC ION, SULFATE ION, ... (6 entities in total) |
| Functional Keywords | metallo-beta-lactamase, zn-dependent hydrolase, antibiotic resistance, hydrolase, metal-binding |
| Biological source | Bacillus cereus |
| Cellular location | Periplasm : P04190 |
| Total number of polymer chains | 4 |
| Total formula weight | 101762.19 |
| Authors | Medrano Martin, F.J.,Gonzalez, J.M.,Vila, A.J. (deposition date: 2009-11-12, release date: 2010-11-24, Last modification date: 2024-02-21) |
| Primary citation | Gonzalez, J.M.,Meini, M.R.,Tomatis, P.E.,Medrano Martin, F.J.,Cricco, J.A.,Vila, A.J. Metallo-beta-lactamases withstand low Zn(II) conditions by tuning metal-ligand interactions. Nat.Chem.Biol., 8:698-700, 2012 Cited by PubMed: 22729148DOI: 10.1038/nchembio.1005 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.58 Å) |
Structure validation
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