4V7J

Structure of RelE nuclease bound to the 70S ribosome (precleavage state)

This is a non-PDB format compatible entry.

Summary for 4V7J

• Entry DOI: 10.2210/pdb4v7j/pdb
• Related: 3KIU 3KIW 3KIX 3KIY
• Descriptor: 30S ribosomal protein S2, 30S ribosomal protein S11, 30S ribosomal protein S12, ... (60 entities in total)
• Functional Keywords: ribosome, rele, nuclease, ribonucleoprotein, ribosomal protein, rna-binding, rrna-binding, metal-binding, zinc-finger, trna-binding, antibiotic resistance, repressor, stress response, toxin, translation, translation regulation
• Biological source: Escherichia coli K-12; More
• Total number of polymer chains: 116
• Total formula weight: 4532553.44

Authors

Neubauer, C.,Gao, Y.-G.,Andersen, K.R.,Dunham, C.M.,Kelley, A.C.,Hentschel, J.,Gerdes, K.,Ramakrishnan, V.,Brodersen, D.E. (deposition date: 2009-11-02, release date: 2014-07-09, Last modification date: 2023-09-20)

• Primary citation: Neubauer, C.,Gao, Y.G.,Andersen, K.R.,Dunham, C.M.,Kelley, A.C.,Hentschel, J.,Gerdes, K.,Ramakrishnan, V.,Brodersen, D.E.; The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.; Cell(Cambridge,Mass.), 139:1084-1095, 2009; PubMed: 20005802; DOI: 10.1016/j.cell.2009.11.015

Experimental method

X-RAY DIFFRACTION (3.3 Å)