3KIO
mouse RNase H2 complex
Summary for 3KIO
Entry DOI | 10.2210/pdb3kio/pdb |
Descriptor | Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C, ... (4 entities in total) |
Functional Keywords | ribonuclease, aicardi-goutieres syndrome, rnase h2, protein complex, autoimmune disease, endonuclease, hydrolase, metal-binding, nuclease, nucleus, phosphoprotein, acetylation |
Biological source | Mus musculus (mouse) More |
Cellular location | Nucleus (By similarity): Q9CWY8 Q80ZV0 Q9CQ18 |
Total number of polymer chains | 3 |
Total formula weight | 89509.58 |
Authors | Shaban, N.,Harvey, S.,Perrino, F.W.,Hollis, T. (deposition date: 2009-11-02, release date: 2009-11-17, Last modification date: 2011-07-13) |
Primary citation | Shaban, N.M.,Harvey, S.,Perrino, F.W.,Hollis, T. The structure of the mammalian RNase H2 complex provides insight into RNA:DNA hybrid processing to prevent immune dysfunction. J.Biol.Chem., 285:3617-3624, 2010 Cited by PubMed: 19923215DOI: 10.1074/jbc.M109.059048 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
Download full validation report