3K24
Crystal structure of mature apo-Cathepsin L C25A mutant in complex with Gln-Leu-Ala peptide
Summary for 3K24
Entry DOI | 10.2210/pdb3k24/pdb |
Related | 3IV2 |
Descriptor | Cathepsin L1, H3 peptide, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-6)-beta-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | co-crystal, substrate, protease, structural genomics, structural genomics consortium, sgc, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 50315.26 |
Authors | Adams-Cioaba, M.A.,Krupa, J.C.,Mort, J.S.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2009-09-29, release date: 2010-03-23, Last modification date: 2023-09-06) |
Primary citation | Adams-Cioaba, M.A.,Krupa, J.C.,Xu, C.,Mort, J.S.,Min, J. Structural basis for the recognition and cleavage of histone H3 by cathepsin L. Nat Commun, 2:197-197, 2011 Cited by PubMed: 21326229DOI: 10.1038/ncomms1204 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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