3J6J
3.6 Angstrom resolution MAVS filament generated from helical reconstruction
Summary for 3J6J
Entry DOI | 10.2210/pdb3j6j/pdb |
EMDB information | 5922 5925 |
Descriptor | Mitochondrial antiviral-signaling protein (1 entity in total) |
Functional Keywords | card, mavs, innate immunity, rig-i, mda5, spontaneous filament formation, seeded filament formation, immune system |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 8 |
Total formula weight | 90414.56 |
Authors | Wu, B.,Peisley, A.,Li, Z.,Egelman, E.,Walz, T.,Penczek, P.,Hur, S. (deposition date: 2014-03-13, release date: 2014-07-30, Last modification date: 2024-02-21) |
Primary citation | Wu, B.,Peisley, A.,Tetrault, D.,Li, Z.,Egelman, E.H.,Magor, K.E.,Walz, T.,Penczek, P.A.,Hur, S. Molecular Imprinting as a Signal-Activation Mechanism of the Viral RNA Sensor RIG-I. Mol.Cell, 55:511-523, 2014 Cited by PubMed: 25018021DOI: 10.1016/j.molcel.2014.06.010 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.64 Å) |
Structure validation
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