Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3IW7

Human p38 MAP Kinase in Complex with an Imidazo-pyridine

Summary for 3IW7
Entry DOI10.2210/pdb3iw7/pdb
Related3IW5 3IW6 3IW8
DescriptorMitogen-activated protein kinase 14, octyl beta-D-glucopyranoside, 2-({4-[(4-benzylpiperidin-1-yl)carbonyl]benzyl}sulfanyl)-3H-imidazo[4,5-c]pyridine, ... (4 entities in total)
Functional Keywordsdfg-out, type-i, alternative splicing, atp-binding, cytoplasm, kinase, nucleotide-binding, nucleus, phosphoprotein, polymorphism, serine/threonine-protein kinase, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight42554.66
Authors
Gruetter, C.,Simard, J.R.,Rauh, D. (deposition date: 2009-09-02, release date: 2009-11-17, Last modification date: 2023-11-01)
Primary citationSimard, J.R.,Gruetter, C.,Pawar, V.,Aust, B.,Wolf, A.,Rabiller, M.,Wulfert, S.,Robubi, A.,Kluter, S.,Ottmann, C.,Rauh, D.
High-Throughput Screening To Identify Inhibitors Which Stabilize Inactive Kinase Conformations in p38alpha
J.Am.Chem.Soc., 131:18478-18488, 2009
Cited by
PubMed: 19950957
DOI: 10.1021/ja907795q
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon