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3IDY

Crystal structure of HIV-gp120 core in complex with CD4-binding site antibody b13, space group C2221

Summary for 3IDY
Entry DOI10.2210/pdb3idy/pdb
Related3IDX
DescriptorHIV-1 HxBc2 gp120 core, Fab b13 heavy chain, Fab b13 light chain, ... (6 entities in total)
Functional Keywordshiv-1, antibody, gp120, b13, envelope glycan protein, cd4-binding site, aids, apoptosis, cell membrane, cleavage on pair of basic residues, disulfide bond, envelope protein, fusion protein, host-virus interaction, membrane, transmembrane, viral immunoevasion, virion, immune system
Biological sourceHuman immunodeficiency virus 1
More
Total number of polymer chains6
Total formula weight173443.74
Authors
Primary citationChen, L.,Do Kwon, Y.,Zhou, T.,Wu, X.,O'Dell, S.,Cavacini, L.,Hessell, A.J.,Pancera, M.,Tang, M.,Xu, L.,Yang, Z.Y.,Zhang, M.Y.,Arthos, J.,Burton, D.R.,Dimitrov, D.S.,Nabel, G.J.,Posner, M.R.,Sodroski, J.,Wyatt, R.,Mascola, J.R.,Kwong, P.D.
Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
Science, 326:1123-1127, 2009
Cited by
PubMed: 19965434
DOI: 10.1126/science.1175868
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.2 Å)
Structure validation

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