3H60
Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c)with two Mn2+ atoms
Summary for 3H60
Entry DOI | 10.2210/pdb3h60/pdb |
Related | 3H61 3H62 3H63 3H64 3H66 3H67 3H68 3H69 |
Descriptor | Serine/threonine-protein phosphatase 5, MANGANESE (II) ION (3 entities in total) |
Functional Keywords | metalloenzymes, phosphatase, cytoplasm, hydrolase, iron, manganese, metal-binding, nucleus, protein phosphatase, tpr repeat |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P53041 |
Total number of polymer chains | 2 |
Total formula weight | 72121.35 |
Authors | Bertini, I.,Calderone, V.,Fragai, M.,Luchinat, C.,Talluri, E. (deposition date: 2009-04-23, release date: 2009-09-29, Last modification date: 2023-11-01) |
Primary citation | Bertini, I.,Calderone, V.,Fragai, M.,Luchinat, C.,Talluri, E. Structural basis of serine/threonine phosphatase inhibition by the archetypal small molecules cantharidin and norcantharidin J.Med.Chem., 52:4838-4843, 2009 Cited by PubMed: 19601647DOI: 10.1021/jm900610k PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report