3GLX

Crystal Structure Analysis of the DtxR(E175K) complexed with Ni(II)

Summary for 3GLX

Entry DOI	10.2210/pdb3glx/pdb
Related	1ddn 1p92 1xcv 2qq9 2qqa 2qqb
Descriptor	Diphtheria toxin repressor, NICKEL (II) ION, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	repressor, regulator, dtxr, helix-turn-helix, metal ion, activation, dna-binding, ferrous iron, cytoplasm, transcription, transcriptional regulation, transcriptional regulator, iron, transcription regulation
Biological source	Corynebacterium diphtheriae
Total number of polymer chains	1
Total formula weight	25531.58
Authors	D'Aquino, J.A.,Denninger, A.,Moulin, A.,D'Aquino, K.E.,Ringe, D. (deposition date: 2009-03-12, release date: 2009-06-09, Last modification date: 2023-09-06)
Primary citation	D'Aquino, J.A.,Denninger, A.R.,Moulin, A.G.,D'Aquino, K.E.,Ringe, D. Decreased sensitivity to changes in the concentration of metal ions as the basis for the hyperactivity of DtxR(E175K). J.Mol.Biol., 390:112-123, 2009 Cited by PubMed: 19433095 DOI: 10.1016/j.jmb.2009.05.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation