3GJO

Crystal structure of human EB1 in complex with microtubule Tip localization signal peptide of MACF

Summary for 3GJO

Entry DOI	10.2210/pdb3gjo/pdb
Descriptor	Microtubule-associated protein RP/EB family member 1, Dystonin (3 entities in total)
Functional Keywords	eb1 structural motif, +tip protein complex, sxip motiff, apc/dynactin binding protein, microtubule actin cross-linking factor, cell cycle, cell division, mitosis, phosphoprotein, actin-binding calcium, structural protein, microtubule, actin-binding
Biological source	Homo sapiens (Human) More
Cellular location	Cytoplasm, cytoskeleton: Q15691
Total number of polymer chains	8
Total formula weight	45639.09
Authors	Honnappa, S.,Steinmetz, M.O. (deposition date: 2009-03-09, release date: 2009-08-04, Last modification date: 2023-11-01)
Primary citation	Honnappa, S.,Gouveia, S.M.,Weisbrich, A.,Damberger, F.F.,Bhavesh, N.S.,Jawhari, H.,Grigoriev, I.,van Rijssel, F.J.A.,Buey, R.M.,Lawera, A.,Jelesarov, I.,Winkler, F.K.,Wuthrich, K.,Akhmanova, A.,Steinmetz, M.O. An EB1-binding motif acts as a microtubule tip localization signal Cell(Cambridge,Mass.), 138:366-376, 2009 Cited by PubMed: 19632184 DOI: 10.1016/j.cell.2009.04.065 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation