3GJC
Crystal Structure of the E290S mutant of LeuT with bound OG
Summary for 3GJC
Entry DOI | 10.2210/pdb3gjc/pdb |
Related | 3GJD |
Descriptor | Transporter, SODIUM ION, LEUCINE, ... (5 entities in total) |
Functional Keywords | transmembrane transport, neurotransmitter:sodium symport, sodium-coupled transport, nss, aminoacid transport, symport, transmembrane, transport, transport protein |
Biological source | Aquifex aeolicus |
Total number of polymer chains | 2 |
Total formula weight | 117468.57 |
Authors | Winther, A.M.L.,Quick, M.,Javitch, J.A.,Nissen, P. (deposition date: 2009-03-08, release date: 2009-04-28, Last modification date: 2023-11-01) |
Primary citation | Quick, M.,Winther, A.M.L.,Shi, L.,Nissen, P.,Weinstein, H.,Javitch, J.A. Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation Proc.Natl.Acad.Sci.USA, 106:5563-5568, 2009 Cited by PubMed: 19307590DOI: 10.1073/pnas.0811322106 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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