3GIV

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

Summary for 3GIV

Entry DOI	10.2210/pdb3giv/pdb
Related	2V2W 2V2X
Descriptor	HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, HIV-1 peptide, ... (4 entities in total)
Functional Keywords	hiv, mhc, escape, antigen, immune recognition, disulfide bond, glycoprotein, host-virus interaction, immune response, membrane, mhc i, phosphoprotein, transmembrane, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted', immune system
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769
Total number of polymer chains	6
Total formula weight	89723.67
Authors	Stewart-Jones, G.,Iversen, A.K.N.,Jones, E.Y. (deposition date: 2009-03-06, release date: 2009-06-30, Last modification date: 2023-11-01)
Primary citation	Tenzer, S.,Wee, E.,Burgevin, A.,Stewart-Jones, G.,Friis, L.,Lamberth, K.,Chang, C.-H.,Harndahl, M.,Weimershaus, M.,Gerstoft, J.,Akkad, N.,Klenerman, P.,Fugger, L.,Jones, E.Y.,McMichael, A.J.,Buus, S.,Schild, H.,van Endert, P.,Iversen, A.K.N. Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance Nat.Immunol., 10:636-646, 2009 Cited by PubMed: 19412183 DOI: 10.1038/ni.1728 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation