3GCL
Mode of ligand binding and assignment of subsites in mammalian peroxidases: crystal structure of lactoperoxidase complexes with acetyl salycylic acid, salicylhydroxamic acid and benzylhydroxamic acid
Summary for 3GCL
Entry DOI | 10.2210/pdb3gcl/pdb |
Related | 3BXI 3GC1 3GCJ 3GCK |
Descriptor | Lactoperoxidase, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | peroxidase, oxidoreductase, antibiotic, antimicrobial, cleavage on pair of basic residues, glycoprotein, heme, hydrogen peroxide, iron, metal-binding, secreted |
Biological source | Bos taurus (Bovine) |
Total number of polymer chains | 1 |
Total formula weight | 71785.20 |
Authors | Singh, A.K.,Singh, N.,Sinha, M.,Bhushan, A.,Kaur, P.,Sharma, S.,Singh, T.P. (deposition date: 2009-02-22, release date: 2009-03-31, Last modification date: 2023-11-01) |
Primary citation | Singh, A.K.,Singh, N.,Sinha, M.,Bhushan, A.,Kaur, P.,Srinivasan, A.,Sharma, S.,Singh, T.P. Binding modes of aromatic ligands to mammalian heme peroxidases with associated functional implications: crystal structures of lactoperoxidase complexes with acetylsalicylic acid, salicylhydroxamic acid, and benzylhydroxamic acid J.Biol.Chem., 284:20311-20318, 2009 Cited by PubMed: 19465478DOI: 10.1074/jbc.M109.010280 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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