3FJQ

Crystal structure of cAMP-dependent protein kinase catalytic subunit alpha in complex with peptide inhibitor PKI alpha (6-25)

Summary for 3FJQ

• Entry DOI: 10.2210/pdb3fjq/pdb
• Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, MANGANESE (II) ION, ... (5 entities in total)
• Functional Keywords: nucleotide binding, protein kinase activity, protein serine/threonine kinase activity, camp-dependent protein kinase activity, protein binding, atp binding, kinase activity, transferase activity, alternative splicing, atp-binding, camp, cytoplasm, kinase, lipoprotein, myristate, nucleotide-binding, nucleus, phosphoprotein, serine/threonine-protein kinase, transferase, protein kinase inhibitor
• Biological source: Mus musculus (mouse); More
• Cellular location: Cytoplasm . Isoform 2: Cell projection, cilium, flagellum : P05132
• Total number of polymer chains: 2
• Total formula weight: 43500.78

Authors

Kim, C. (deposition date: 2008-12-15, release date: 2009-08-04, Last modification date: 2017-11-01)

• Primary citation: Thompson, E.E.,Kornev, A.P.,Kannan, N.,Kim, C.,Ten Eyck, L.F.,Taylor, S.S.; Comparative surface geometry of the protein kinase family.; Protein Sci., 18:2016-2026, 2009; PubMed: 19610074; DOI: 10.1002/pro.209

Experimental method

X-RAY DIFFRACTION (1.6 Å)