3EKC
structure of W60V beta-2 microglobulin mutant
Summary for 3EKC
Entry DOI | 10.2210/pdb3ekc/pdb |
Related | 2Z9T |
Descriptor | Beta-2-microglobulin (2 entities in total) |
Functional Keywords | beta-2-microglobulin, tryptophan, glycine, amyloidosis, dra, beta fibrils, disease mutation, glycation, glycoprotein, immune response, immunoglobulin domain, mhc i, pyrrolidone carboxylic acid, secreted, immune system |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: P61769 |
Total number of polymer chains | 1 |
Total formula weight | 11792.28 |
Authors | Ricagno, S.,Sangiovanni, E.,Bellotti, V.,Bolognesi, M. (deposition date: 2008-09-19, release date: 2009-05-26, Last modification date: 2023-11-01) |
Primary citation | Ricagno, S.,Raimondi, S.,Giorgetti, S.,Bellotti, V.,Bolognesi, M. Human beta-2 microglobulin W60V mutant structure: Implications for stability and amyloid aggregation Biochem.Biophys.Res.Commun., 380:543-547, 2009 Cited by PubMed: 19284997DOI: 10.1016/j.bbrc.2009.01.116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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