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3ECW

Crystal structure of the ALS-related pathological mutant T54R of human apo Cu,Zn Superoxide Dismutase (SOD1)

Summary for 3ECW
Entry DOI10.2210/pdb3ecw/pdb
Related3ECU 3ECV
DescriptorSuperoxide dismutase [Cu-Zn] (2 entities in total)
Functional Keywordshuman superoxide dismutase, homodimeric protein, apo protein, aggregation, als, mutant, acetylation, amyotrophic lateral sclerosis, antioxidant, copper, cytoplasm, disease mutation, metal-binding, oxidoreductase, ubl conjugation, zinc
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm: P00441
Total number of polymer chains4
Total formula weight63534.60
Authors
Calderone, V. (deposition date: 2008-09-02, release date: 2009-05-19, Last modification date: 2023-08-30)
Primary citationBanci, L.,Bertini, I.,Boca, M.,Calderone, V.,Cantini, F.,Girotto, S.,Vieru, M.
Structural and dynamic aspects related to oligomerization of apo SOD1 and its mutants.
Proc.Natl.Acad.Sci.USA, 106:6980-6985, 2009
Cited by
PubMed: 19369197
DOI: 10.1073/pnas.0809845106
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.15 Å)
Structure validation

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