3E6P

Crystal structure of human meizothrombin desF1

Summary for 3E6P

Entry DOI	10.2210/pdb3e6p/pdb
Related	1A0H
Descriptor	Prothrombin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (7 entities in total)
Functional Keywords	thrombin, meizothrombin, allostery, linkage, na+ binding, acute phase, blood coagulation, cleavage on pair of basic residues, disease mutation, gamma-carboxyglutamic acid, glycoprotein, hydrolase, kringle, protease, secreted, serine protease, zymogen
Biological source	Homo sapiens More
Total number of polymer chains	2
Total formula weight	48328.36
Authors	Papaconstantinou, M.E.,Gandhi, P.,Chen, Z.,Bah, A.,Di Cera, E. (deposition date: 2008-08-15, release date: 2008-11-18, Last modification date: 2023-08-30)
Primary citation	Papaconstantinou, M.E.,Gandhi, P.S.,Chen, Z.,Bah, A.,Di Cera, E. Na(+) binding to meizothrombin desF1. Cell.Mol.Life Sci., 65:3688-3697, 2008 Cited by PubMed: 18854941 DOI: 10.1007/s00018-008-8502-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation