3DL4

Non-Aged Form of Mouse Acetylcholinesterase Inhibited by Tabun- Update

Summary for 3DL4

Entry DOI	10.2210/pdb3dl4/pdb
Related	2c0p 2c0q 3DJY 3DKK 3DL7
Descriptor	Acetylcholinesterase, HEXAETHYLENE GLYCOL (3 entities in total)
Functional Keywords	hydrolase, tabun, organophosphate, aging, alternative splicing, cell junction, glycoprotein, gpi-anchor, lipoprotein, membrane, neurotransmitter degradation, secreted, serine esterase, synapse
Biological source	Mus musculus (mouse)
Cellular location	Cell junction, synapse. Isoform H: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side: P21836
Total number of polymer chains	2
Total formula weight	121020.50
Authors	Carletti, E.,Li, H.,Li, B.,Ekstrom, F.,Nicolet, Y.,Loiodice, M.,Gillon, E.,Froment, M.T.,Lockridge, O.,Schopfer, L.M.,Masson, P.,Nachon, F. (deposition date: 2008-06-26, release date: 2008-12-02, Last modification date: 2021-03-31)
Primary citation	Carletti, E.,Li, H.,Li, B.,Ekstrom, F.,Nicolet, Y.,Loiodice, M.,Gillon, E.,Froment, M.T.,Lockridge, O.,Schopfer, L.M.,Masson, P.,Nachon, F. Aging of Cholinesterases Phosphylated by Tabun Proceeds through O-Dealkylation. J.Am.Chem.Soc., 130:16011-16020, 2008 Cited by PubMed: 18975951 DOI: 10.1021/ja804941z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation