3DJI
Crystal Structure of Macrophage Migration Inhibitory Factor Bound to an Acetaminophen Dimer Derived from NAPQI
Summary for 3DJI
Entry DOI | 10.2210/pdb3dji/pdb |
Related | 1GD0 1MIF 3CE4 3DJH |
Descriptor | Macrophage migration inhibitory factor, CHLORIDE ION, N,N'-(6,6'-dihydroxybiphenyl-3,3'-diyl)diacetamide, ... (4 entities in total) |
Functional Keywords | homotrimer, acetaminophen dimer, cytokine, inflammatory response, isomerase, phosphoprotein |
Biological source | Homo sapiens |
Cellular location | Secreted : P14174 |
Total number of polymer chains | 6 |
Total formula weight | 74962.44 |
Authors | Crichlow, G.V.,Lolis, E. (deposition date: 2008-06-23, release date: 2008-12-23, Last modification date: 2023-08-30) |
Primary citation | Crichlow, G.V.,Lubetsky, J.B.,Leng, L.,Bucala, R.,Lolis, E.J. Structural and kinetic analyses of macrophage migration inhibitory factor active site interactions. Biochemistry, 48:132-139, 2009 Cited by PubMed: 19090677DOI: 10.1021/bi8014423 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
Download full validation report