3DJF
Crystal Structure of Schistosoma mansoni Purine Nucleoside Phosphorylase in a complex with BCX-34
Summary for 3DJF
Entry DOI | 10.2210/pdb3djf/pdb |
Related | 1tcu 1tcv 1td1 |
Descriptor | Purine-nucleoside phosphorylase, SULFATE ION, DIMETHYL SULFOXIDE, ... (5 entities in total) |
Functional Keywords | purine nucleoside phosphorylase, bcx34, inhibitor, glycosyltransferase, transferase |
Biological source | Schistosoma mansoni (Blood fluke) |
Total number of polymer chains | 3 |
Total formula weight | 94742.03 |
Authors | Postigo, M.P.,Pereira, H.M.,Oliva, G.,Andricopulo, A.D. (deposition date: 2008-06-23, release date: 2009-06-30, Last modification date: 2024-02-21) |
Primary citation | Castilho, M.S.,Postigo, M.P.,Pereira, H.M.,Oliva, G.,Andricopulo, A.D. Structural basis for selective inhibition of purine nucleoside phosphorylase from Schistosoma mansoni: kinetic and structural studies. Bioorg.Med.Chem., 18:1421-1427, 2010 Cited by PubMed: 20129792DOI: 10.1016/j.bmc.2010.01.022 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.302 Å) |
Structure validation
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