3DHO

Structure of Streptogramin Acetyltransferase in Complex with an Inhibitor

Summary for 3DHO

• Entry DOI: 10.2210/pdb3dho/pdb
• Related: 1KHR
• Descriptor: Streptogramin A acetyltransferase, DIMETHYL SULFOXIDE, 6-bromo-N'-[(1Z)-(3,5-dichloro-2-hydroxyphenyl)methylidene]-2-methylquinoline-4-carbohydrazide, ... (5 entities in total)
• Functional Keywords: streptogramin acetyltransferase left-handed parallel beta helix, acyltransferase, antibiotic resistance, transferase
• Biological source: Enterococcus faecium (Streptococcus faecium)
• Total number of polymer chains: 6
• Total formula weight: 145653.68

Authors

Roderick, S.L.,Pesaresi, A.,Wright, G.D. (deposition date: 2008-06-18, release date: 2009-09-22, Last modification date: 2023-08-30)

• Primary citation: Johnston, N.J.,Blanchard, J.E.,Koteva, K.P.,Ejim, L.J.,Pesaresi, A.,Roderick, S.L.,Wright, G.D.; Structure of Streptogramin Acetyltransferase in Complex with an Inhibitor; To be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)