3CXD
Crystal structure of anti-osteopontin antibody 23C3 in complex with its epitope peptide
Summary for 3CXD
Entry DOI | 10.2210/pdb3cxd/pdb |
Descriptor | Fab fragment of anti-osteopontin antibody 23C3, Light chain, Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, a peptide from osteopontin, ... (4 entities in total) |
Functional Keywords | fab, osteopontin, opn, antibody-antigen complex, immune system |
Biological source | Mus musculus (mouse) More |
Cellular location | Secreted: P10451 |
Total number of polymer chains | 3 |
Total formula weight | 48307.53 |
Authors | |
Primary citation | Du, J.,Hou, S.,Zhong, C.,Lai, Z.,Yang, H.,Dai, J.,Zhang, D.,Wang, H.,Guo, Y.,Ding, J. Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis J.Mol.Biol., 382:835-842, 2008 Cited by PubMed: 18694758DOI: 10.1016/j.jmb.2008.07.075 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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