3CV5

GOLGI MANNOSIDASE II D204A catalytic nucleophile mutant complex with 3alpha,6alpha-mannopentaose

Summary for 3CV5

Entry DOI	10.2210/pdb3cv5/pdb
Related	1HTY 1HWW 1HXK 1PS2 1QWN 1QWU 1QX1 1R33 1R34 2ALW 2F7O 2F7P 2F7Q 2F7R 3BUB 3BUD 3BUI 3BUP 3BUQ 3BVT 3BVU 3BVV 3BVW 3BVX
Descriptor	Alpha-mannosidase 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	family 38 glycosyl hydrolase, glycosidase, golgi apparatus, membrane, metal-binding, signal-anchor, transmembrane, hydrolase
Biological source	Drosophila melanogaster (Fruit fly)
Total number of polymer chains	1
Total formula weight	120891.11
Authors	Shah, N.,Kuntz, D.A.,Rose, D.R. (deposition date: 2008-04-17, release date: 2008-06-24, Last modification date: 2023-08-30)
Primary citation	Shah, N.,Kuntz, D.A.,Rose, D.R. Golgi alpha-mannosidase II cleaves two sugars sequentially in the same catalytic site. Proc.Natl.Acad.Sci.Usa, 105:9570-9575, 2008 Cited by PubMed: 18599462 DOI: 10.1073/pnas.0802206105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation