3CHB

CHOLERA TOXIN B-PENTAMER COMPLEXED WITH GM1 PENTASACCHARIDE

Summary for 3CHB

• Entry DOI: 10.2210/pdb3chb/pdb
• Descriptor: CHOLERA TOXIN, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: toxin, toxin-receptor complex, pentasaccharide
• Biological source: Vibrio cholerae
• Cellular location: Secreted: P01556
• Total number of polymer chains: 5
• Total formula weight: 64288.48

Authors

Merritt, E.A.,Hol, W.G.J. (deposition date: 1998-03-24, release date: 1998-08-12, Last modification date: 2023-08-09)

• Primary citation: Merritt, E.A.,Kuhn, P.,Sarfaty, S.,Erbe, J.L.,Holmes, R.K.,Hol, W.G.; The 1.25 A resolution refinement of the cholera toxin B-pentamer: evidence of peptide backbone strain at the receptor-binding site.; J.Mol.Biol., 282:1043-1059, 1998; PubMed: 9753553; DOI: 10.1006/jmbi.1998.2076

Experimental method

X-RAY DIFFRACTION (1.25 Å)