3B68
Crystal structure of the androgen receptor ligand binding domain in complex with SARM S-4
Summary for 3B68
Entry DOI | 10.2210/pdb3b68/pdb |
Related | 2AXA 3B5R 3B65 3B66 3B67 |
Descriptor | Androgen receptor, (2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide (3 entities in total) |
Functional Keywords | androgen receptor, sarm, disease mutation, dna-binding, lipid-binding, metal-binding, nucleus, polymorphism, steroid-binding, transcription, transcription regulation, triplet repeat expansion, ubl conjugation, zinc, zinc-finger |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus: P10275 |
Total number of polymer chains | 1 |
Total formula weight | 29487.43 |
Authors | Bohl, C.E.,Miller, D.D.,Dalton, J.T. (deposition date: 2007-10-27, release date: 2008-09-09, Last modification date: 2023-08-30) |
Primary citation | Bohl, C.E.,Wu, Z.,Chen, J.,Mohler, M.L.,Yang, J.,Hwang, D.J.,Mustafa, S.,Miller, D.D.,Bell, C.E.,Dalton, J.T. Effect of B-ring substitution pattern on binding mode of propionamide selective androgen receptor modulators Bioorg.Med.Chem.Lett., 18:5567-5570, 2008 Cited by PubMed: 18805694DOI: 10.1016/j.bmcl.2008.09.002 PDB entries with the same primary citation |
Experimental method |
Structure validation
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