3AP9

Crystal structure of the galectin-8 N-terminal carbohydrate recognition domain in complex with Lacto-N-fucopentaose III

Summary for 3AP9

Entry DOI	10.2210/pdb3ap9/pdb
Related	3AP4 3AP5 3AP6 3AP7 3APB
Descriptor	Galectin-8, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total)
Functional Keywords	beta-sandwich, galectin, carbohydrate/sugar binding, lacto-n-fucopentaose iii, sugar binding protein
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm (Probable): O00214
Total number of polymer chains	1
Total formula weight	18501.43
Authors	Matsuzaka, T.,Ideo, H.,Yamashita, K.,Nonaka, T. (deposition date: 2010-10-12, release date: 2011-02-02, Last modification date: 2023-11-01)
Primary citation	Ideo, H.,Matsuzaka, T.,Nonaka, T.,Seko, A.,Yamashita, K. Galectin-8-N-domain recognition mechanism for sialylated and sulfated glycans J.Biol.Chem., 286:11346-11355, 2011 Cited by PubMed: 21288902 DOI: 10.1074/jbc.M110.195925 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.33 Å)

Structure validation