3ANM

Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) complexed with 5-phenylpyridin-2-ylmethylphosphonic acid

Summary for 3ANM

Entry DOI	10.2210/pdb3anm/pdb
Related	1JVS 1T1R 1T1S 2EGH 3ANL 3ANN
Descriptor	1-deoxy-D-xylulose 5-phosphate reductoisomerase, [(5-phenylpyridin-2-yl)methyl]phosphonic acid, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
Functional Keywords	reductoisomerase, nadph binding, oxidoreductase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	93482.00
Authors	Endo, K.,Kato, M.,Deng, L.,Song, Y.,Yajima, S. (deposition date: 2010-09-03, release date: 2011-02-23, Last modification date: 2023-11-01)
Primary citation	Deng, L.,Endo, K.,Kato, M.,Cheng, G.,Yajima, S.,Song, Y. Structures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate Complexes ACS Med Chem Lett, 2:165-170, 2011 Cited by PubMed: 21379374 DOI: 10.1021/ml100243r PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation