3AEZ

Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with GDP and Phosphopantothenate

Summary for 3AEZ

Entry DOI	10.2210/pdb3aez/pdb
Related	2ZS8 2ZS9 2ZSA 2ZSB 2ZSE 2ZSF 3AF0 3AF1 3AF2 3AF3 3AF4
Descriptor	Pantothenate kinase, GUANOSINE-5'-DIPHOSPHATE, N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanine, ... (6 entities in total)
Functional Keywords	transferase, homodimer, coa biosynthesis, nucleotide binding, atp-binding, kinase, nucleotide-binding
Biological source	Mycobacterium tuberculosis
Cellular location	Cytoplasm (By similarity): P63810
Total number of polymer chains	1
Total formula weight	37667.48
Authors	Chetnani, B.,Kumar, P.,Surolia, A.,Vijayan, M. (deposition date: 2010-02-18, release date: 2010-05-26, Last modification date: 2023-11-01)
Primary citation	Chetnani, B.,Kumar, P.,Surolia, A.,Vijayan, M. M. tuberculosis pantothenate kinase: dual substrate specificity and unusual changes in ligand locations J.Mol.Biol., 400:171-185, 2010 Cited by PubMed: 20451532 DOI: 10.1016/j.jmb.2010.04.064 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation