3AA0

Crystal structure of Actin Capping Protein in complex with the Cp-binding motif derived from CARMIL

Summary for 3AA0

Entry DOI	10.2210/pdb3aa0/pdb
Related	1IZN 3AA1 3AA6 3AA7 3AAA 3AAE
Descriptor	F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1 and 2, 21mer peptide from Leucine-rich repeat-containing protein 16A, ... (5 entities in total)
Functional Keywords	actin capping protein, barbed end regulation, carmil family protein, conformational change, cell motility, actin capping, actin-binding, cytoskeleton, isopeptide bond, leucine-rich repeat, protein binding
Biological source	Gallus gallus (Chicken) More
Cellular location	Cytoplasm, myofibril, sarcomere, Z line: P13127 Isoform 1: Cytoplasm, myofibril, sarcomere, Z line . Isoform 2: Cytoplasm, myofibril, sarcomere, I band : P14315 Cytoplasm : Q6EDY6
Total number of polymer chains	3
Total formula weight	63147.94
Authors	Takeda, S.,Minakata, S.,Narita, A.,Kitazawa, M.,Yamakuni, T.,Maeda, Y.,Nitanai, Y. (deposition date: 2009-11-11, release date: 2010-08-04, Last modification date: 2023-11-01)
Primary citation	Takeda, S.,Minakata, S.,Koike, R.,Kawahata, I.,Narita, A.,Kitazawa, M.,Ota, M.,Yamakuni, T.,Maeda, Y.,Nitanai, Y. Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition Plos Biol., 8:e1000416-e1000416, 2010 Cited by PubMed: 20625546 DOI: 10.1371/journal.pbio.1000416 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation