3A1L

Crystal Structure of 11,11'-Dichlorochromopyrrolic Acid Bound Cytochrome P450 StaP (CYP245A1)

Summary for 3A1L

Entry DOI	10.2210/pdb3a1l/pdb
Related	2z3t 2z3u
Descriptor	Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, 3,4-bis(7-chloro-1H-indol-3-yl)-1H-pyrrole-2,5-dicarboxylic acid, ... (4 entities in total)
Functional Keywords	oxidoreductase, cytochrome p450, monooxygenase, heme-enzyme, heme, iron, metal-binding
Biological source	Streptomyces sp. TP-A0274
Total number of polymer chains	1
Total formula weight	48333.01
Authors	Makino, M.,Sugimoto, H.,Shiro, Y.,Asamizu, S.,Onaka, H.,Nagano, S. (deposition date: 2009-04-09, release date: 2009-05-12, Last modification date: 2023-11-01)
Primary citation	Wang, Y.,Chen, H.,Makino, M.,Shiro, Y.,Nagano, S.,Asamizu, S.,Onaka, H.,Shaik, S. Theoretical and experimental studies of the conversion of chromopyrrolic acid to an antitumor derivative by cytochrome P450 StaP: the catalytic role of water molecules J.Am.Chem.Soc., 131:6748-6762, 2009 Cited by PubMed: 19385626 DOI: 10.1021/ja9003365 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation