360D

STRUCTURE OF 2,5-BIS{[4-(N-ETHYLAMIDINO)PHENYL]}FURAN COMPLEXED TO 5'-D(CPGPCPGPAPAPTPTPCPGPCPG)-3'. A MINOR GROOVE DRUG COMPLEX, SHOWING PATTERNS OF GROOVE HYDRATION

Summary for 360D

• Entry DOI: 10.2210/pdb360d/pdb
• Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION, N,N'-(furan-2,5-diylbis{benzene-4,1-diyl[(Z)-aminomethylylidene]})diethanaminium, ... (4 entities in total)
• Functional Keywords: b-dna, double helix, complexed with drug, dna
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 7713.56

Authors

Guerri, A.,Simpson, I.J.,Neidle, S. (deposition date: 1997-10-29, release date: 1998-07-16, Last modification date: 2023-08-02)

• Primary citation: Guerri, A.,Simpson, I.J.,Neidle, S.; Visualisation of extensive water ribbons and networks in a DNA minor-groove drug complex.; Nucleic Acids Res., 26:2873-2878, 1998; PubMed: 9611230; DOI: 10.1093/nar/26.12.2873

Experimental method

X-RAY DIFFRACTION (1.85 Å)