302D
META-HYDROXY ANALOGUE OF HOECHST 33258 ('HYDROXYL IN' CONFORMATION) BOUND TO D(CGCGAATTCGCG)2
Summary for 302D
Entry DOI | 10.2210/pdb302d/pdb |
Descriptor | DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), 3-[5-[5-(4-METHYL-PIPERAZIN-1-YL)-1H-IMIDAZO[4,5-B]PYRIDIN-2-YL]-BENZIMIDAZOL-2-YL]-PHENOL, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | b-dna, double helix, complexed with drug, dna |
Total number of polymer chains | 2 |
Total formula weight | 7776.57 |
Authors | Clark, G.R.,Squire, C.J.,Gray, E.J.,Leupin, W.,Neidle, S. (deposition date: 1996-06-26, release date: 1997-01-20, Last modification date: 2024-04-03) |
Primary citation | Clark, G.R.,Squire, C.J.,Gray, E.J.,Leupin, W.,Neidle, S. Designer DNA-binding drugs: the crystal structure of a meta-hydroxy analogue of Hoechst 33258 bound to d(CGCGAATTCGCG)2. Nucleic Acids Res., 24:4882-4889, 1996 Cited by PubMed: 9017011DOI: 10.1093/nar/24.24.4882 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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